Lease this WebApp and get rid of the ads.
Genetic links to meningioma, long from AMB
Sat Feb 11, 2012 01:55

MY dear Meningimates,

I'm sharing links to information I wanted to find for my own health and future wellness for me, my siblings and especially my three kids and grandson. I hope I can also help educate you and perhaps we can alert more of our doctors too.

I'm worried these long reports below might be too much information or too scary for some of us or our loved ones at the time of medical treatment crisis. I really do not want to overwhelm anyone about potential genetic risks for our family members either.

Surfing around I found four inherited diseases related to meningioma development. You can take these reports below to your own medical team and share them with your family members if you want, or just file them for when you or your loved ones have time to read.

From your own emails, it seems to me that most of our doctors do not share this type of genetic neurofibromatosis background info with you to keep your eyes open for any symptoms in your own relatives, At the DIA conference last fall I met several young parents of little kids with neurofibromatosis NF2 and they didn't seem to know it strikes older adults like us too. That apparent medical knowledge gap in their parents made me even more curious about the genetic links to meningioma.

http://insciences.org/article.php?article_id=10259

This European article above says relatives of people with meningiomas are three times more likely to develop this disease than other people. Lifestyle choices and other specific environmental factors besides prior radiation exposure seem to add to some individuals inherited disease risk.

I'd like to propose my own theory that prior exposure to radiation or cancer in either parent or grandparent before they have their own children might contribute to inherited cancer susceptability in DNA mutations. These genetic mutations could increase total cummulative lifetime radiation risk and might explain the cancer mutations in my siblings. My Dad died of prostate cancer, 3 of my siblings have had cancer now and neither of my parents or 5 siblings have had meningioma, but me and my 3 sisters and my Mom have all had uterine fibroids and gall bladder disease.

So far only a small proportion of meningiomas are directly linked to inherited genetic diseases and some are related to the late longterm effects of previous ionizing radiation exposure. These four inherited diseases can cause a wide variety of low grade abnormal cell growth masses, benign lumps and bumps, cysts, adenomas, lesions, neoplasms and solid tumors or meningiomas before they progress to cancer.

The first one is von Rechlinghausen disease or Neurofibromatosis Type One and Two, NF1 and NF2, and three other rare genetic mutations that can cause meningiomas are called Cowden syndrome, Werner syndrome and Gorlin syndrome.

I added four reliable medical links below to read more about the potential disease progression of each one...
Studying our genetic history now is like studying our family history and the extra reading can be good cognitive therapy for "normal" people too. lol
(My sarcasm above is optional comedy like what MAXINE said about her yellow file folders made me laugh in the Hallmark store yesterday.
MAXINE says "Everyone has a right to MY OPINION.")LOL

http://www.ninds.nih.gov/disorders/neurofibromatosis/neurofibromatosis.htm

http://www.cancer.net/patient/Cancer+Types/Cowden+Syndrome

http://emedicine.medscape.com/article/1114125-clinical#a0217

http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002423/

GBYAY Anne McGinnis Breen
See my ponytail bouncing and my smiley face winking at you? &;>)

Any new readers please scroll all the way down to my first two blog entries for my list of 28 questions to ask your medical team about brain tumor treatments plus my personal meningioma alternative drug therapy RU486 Mifepristone and my new blog comments about the obsolete 1990s EPA radiation risk calculations for women and children are found at http://gbyay.blogspot.com
~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~
Keep you faith, cherish your reason, treasure your mind and hold to your own good purpose...be not afraid!

    • thank you Annesharon booker, Thu Feb 16 05:51
      Anne -- thank you for your tireless research. This is where you are at your best. Wishing you and our meningimates good health. Sharon
  • Click here to receive daily updates