we picked up our puppy at 9 weeks from the breeder and drove the 3 hr drive back home with the new puppy in my arms, on my lap, loving her and letting her sleep. She threw up a very small amount about halfway into the trip (maybe carsick?) and hasn't done that since. She slept a lot when we got home. Before we left the breeder's, she pee'd on their grass. We stopped once on the ride home and she pee'd then, and she pee'd after we got home.
We wanted to change her food from the breeder's purina puppy kibble to Blue Buffalo, so we did that gradually over the first week or so - no problem.
We started the first night putting her in her crate with most of it's area sectioned off (at 5 mo, the wire divider is now removed). She slept w/out a peep from about 10 until 8 am and still does that.
We went to walmart and bought the "poochie bells" by purina and started using them the second day, toching her nose or pay to them hanging in the door every time we took her out to the yard to poop or pee. By the 2nd day, she was ringing them by jumping up and knocking them with her head or paw whenever she needed to go out. The really work!!!

You won't believe how instantly you'll fall in love and become attached. Enjoy those moments of so many "firsts"!